Gold(I)-Catalyzed Tandem Transformation: A Simple Approach for the Synthesis of Pyrrolo/Pyrido[2,1-a][1,3]benzoxazinones and Pyrrolo/Pyrido[2,1-a] quinazolinones

Enguang Feng, Yu Zhou, Dengyou Zhang, Lei Zhang, Haifeng Sun, Hualiang Jiang

We have developed a simple method for the synthesis of pyrrolo/pyrido[2,1-a][1,3]benzoxazinones
and pyrrolo/pyrido[2,1-a]quinazolinones from 2-amino benzoic acids and 2-amino benzamides via
a gold(I)-catalyzed tandem coupling/cyclization process. The tricyclic or polycyclic molecular architectures
were constructed in one pot with the formation of three new bonds.