Gold(I)-Catalyzed Cascade for Synthesis of Pyrrolo[1,2-a:2',1'-c]/Pyrido[2,1-c]pyrrolo[1,2-a]quinoxalinones

Yu Zhou, Xun Ji, Guannan Liu, Dengyou Zhang, Linxiang Zhao, Hualiang Jiang, and Hong Liu

Abstract: An efficient and convenient method was
developed for the one-pot construction of the complex
polycyclic heterocycles pyrrolo[1,2-a:2',1'-c]-/
pyridoACHTUNGTRENUNG[2,1-c]pyrroloACHTUNGTRENUNG[1,2-a]quinoxalinones from two
simple starting materials via a gold(I)-catalyzed
domino reaction. This strategy presents an atom economical
and environmentally friendly transformation,
in which two new CN bonds and one new C
C bond are formed in a one-pot reaction process.

Keywords: alkynes; aromatic amines; cascade reactions;
gold catalysts; pyrrolo[1,2-a:2',1'-c]-/pyrido-
ACHTUNGTRENUNG[2,1-c]pyrroloACHTUNGTRENUNG[1,2-a]quinoxalinones